The pdif site can mediate the transfer of antibiotic resistance genes(ARGs) within the same plasmid and between different plasmids, and it plays a crucial role in the spread of Acinetobacter baumannii resistance. However, there is currently no annotation method related to identify pdif sites. For this reason, we developed a tool named "pdifFinder" which can identify pdif site, ARG, and pdif modules. The pdifFinder code, standalone software package and description with tutorials are available at https://github.com/mjshao06/pdifFinder.
Please cite: Mengjie Shao, Nanjiao Ying, Qian Liang, Nan Ma, Sebastian Leptihn, Yunsong Yu, Huan Chen, Chengzhi Liu, Xiaoting Hua, Pdif-mediated Antibiotic resistance genes Transfer in Bacteria identified by pdifFinder, Briefings in Bioinformatics, 2022;, bbac521, https://doi.org/10.1093/bib/bbac521.
12/05/2022
PdifFinder paper has been successfully published online in Briefings in Bioinformatics.
11/01/2022
PdifFinder paper has been accepted by Briefings in Bioinformatics.
10/21/2022
Updated the download links of the excel files containing the pdif, pdif modules, and ARGs for each genus in data;
10/19/2022
Improved the analysis piplines in the example data;
08/23/2022
User tutorial is online available;
06/23/2022
The pdifFinder service was launched;